Read epigenetics in human reproduction and development by anna k naumova with rakuten kobo epigenetics is defined as heritable changes that do not affect the dna sequence but influence gene expression epigeneti. Epigenetics in human reproduction and development pdf epigenetics is defined as heritable changes that do not affect the dna sequence but influence gene expression epigenetic changes occur at the levels of dna histone protein and chromatin structures. In this view epigenetic studies represent a breakthrough in the field of human reproduction in fact since epigenetic modifications can be transmitted to the offspring they obviously involve germ cells and in some cases they could affect gametogenesis as well as the embryo development thus representing a potential cause of infertility of . Epigenetic mechanisms play key roles in many biological processes and it has become clear that their disruption can gives rise to diverse pathologies in humans edited by preeminent experts sophie rousseaux and saadi khochbin this volume in the epigenetics and human health series discusses the role of epigenetics in human reproduction. Epigenetic modification has an important role during embryo development health oogenesis and spermatogenesis restriction and specific epigenetic changing in the gene imprinting status and dna methylation can be lead to specific human diseases
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